Self Micro Emulsifying Drug Delivery System - A Capsulization

The aim of the present work is to emphasize about the importance and to make a capsule review on self micro emulsifying drug delivery system. Oral route of drug administration has been the most prominent way of drug delivery system, because of its ability to prepare the formulation in an economical way, easy to administer, does not require any specific storage condition compared with parenteral route of administration. Some products also have the disadvantage of poor solubility of drugs which cause low dissolution rate resulting in low bioavailability. As classified under the BCS, the Class II drugs have low solubility. Many technologies are available to improve the solubility of the drugs such as micronization, dispersion, alteration of pH, conversion into salt forms, etc. Self micro emulsifying drug delivery system is new into these category which ensure improved bioavailability of the drugs and thereby decreases the dosing frequency, the amount to administer and also has the ability to target selective. KeywordsDrug delivery, emulsification, improved bioavailability, SMEDDS, solvents, surfactants,